The population of England and Wales has been assumed to be 50,000,000. The population of the Keyworth practice has been taken as 11,000, although in 1977 it was closer to 11,500, and today it is closer to 10,500
| year | Notified cases England and Wales | Keyworth/100,000 | England & Wales/100,000 | Keyworth cases | Keyworth/England & Wales |
| 1977 | 17475 | 1482 | 35.0 | 163 | 42 |
| 1978 | 65957 | 536 | 131.9 | 59 | 4 |
| 1979 | 30816 | 118 | 61.6 | 13 | 2 |
| 1980 | 21131 | 45 | 42.3 | 5 | 1 |
| 1981 | 19395 | 364 | 38.8 | 40 | 9 |
| 1982 | 62812 | 200 | 125.6 | 22 | 2 |
| 1983 | 19340 | 27 | 38.7 | 3 | 1 |
| 1984 | 5517 | 0 | 11.0 | 0 | 0 |
| 1985 | 22046 | 500 | 44.1 | 55 | 11 |
| 1986 | 36506 | 364 | 73.0 | 40 | 5 |
| 1987 | 15203 | 364 | 30.4 | 40 | 12 |
| 1988 | 5117 | 9 | 10.2 | 1 | 1 |
| 1989 | 11646 | 155 | 23.3 | 17 | 7 |
| 1990 | 15286 | 273 | 30.6 | 30 | 9 |
| 1991 | 5201 | 73 | 10.4 | 8 | 7 |
| 1992 | 2309 | 45 | 4.6 | 5 | 10 |
| 1993 | 4091 | 55 | 8.2 | 6 | 7 |
| 1994 | 3964 | 27 | 7.9 | 3 | 3 |
| 1995 | 1869 | 318 | 3.7 | 35 | 85 |
| 1996 | 2354 | 482 | 4.7 | 53 | 102 |
| 1997 | 2996 | 191 | 6.0 | 21 | 32 |
| 1998 | 1577 | 27 | 3.2 | 3 | 9 |
| 1999 | 1139 | 109 | 2.3 | 12 | 48 |
| 2000 | 712 | 36 | 1.4 | 4 | 26 |
| 2001 | 888 | 55 | 1.8 | 6 | 31 |
| 2002 | 883 | 400 | 1.8 | 44 | 227 |
| 2003 | 409 | 0 | 0.8 | 0 | 0 |
| 2004 | 504 | 27 | 1.0 | 3 | 27 |
| 2005 | 594 | 36 | 1.2 | 4 | 31 |